Self-reported medication adherence was high across all measures. Dupuy: rf. As in the case of an exploratory study, we have not applied correction for multiple comparisons following the recommendations of several authors Bender and Lange, , Rothman, , Savitz and Olshan, , corrections possibly increasing the risk of type II errors.
Dupuy: rf. A fifth exclusion criterion concerned domestic violence which is mostly woman specific, frequently chronic and associated with high prevalence of current PTSD which may introduce a methodological bias regarding causality. Methods 2. Our prospective study aimed to examine the effect of both psychological psychiatric history and peritraumatic reaction and a large range of potential markers of biological diatheses on PTSD onset after 1-month and maintenance 4- and months , in people who have recently experienced a traumatic event of the civilian life, while taking into account sociodemographic pre-trauma factors. This stressor must be sufficiently severe to activate the diathesis and promote the development of PTSD. This self-reported questionnaire includes perceptions of depersonalization, derealization, corporal change, and altered notion of time.
Results Multivariate logistic regression analyses demonstrated both psychological and biological diatheses to be independent risk factors for PTSD. Chi-square tests compared the characteristics of participants included in the analyses with those excluded. However, to our knowledge, no study on PTSD etiology has studied both aspects concurrently. Interviews lasted approximately two hours. Scali: rf.
Implications for interventions are discussed. Sebanne: rf. Chaudieu: rf. The model ability to properly classify the subjects was evaluated using an index of predictive discrimination, the concordance c , that is identical to the area under the curve. Baseline characteristics The median age QQ75 was Furthermore, psychological distress is negatively associated with adherence and overall quality of life.
No other significant differences were found between the participants included in analyses and those lost to follow-up. The models providing the best goodness of fit to the current dataset, as assessed using the Akaike Information Criterion AIC , were selected. The study protocol was approved by the South-Mediterranean Ethics Committee and written informed consent was obtained from each participant.
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