Heteroatom Chem. Capdevielle, P. DeKorver, Whitney L. The separated salts are then reacted with amines to generate the amidines shown in Scheme 4. Amidrazones Amidrazones are weak monoacid bases characterized by the structural formula 74, where R, R', R'', R''' and R'''' can be any of a wide variety of atomic or organic moieties.
From ketimines, acetylenes, and carbodiimides. Thus the reaction of 1,3,4oxathiazoline 3-dioxide in dioxane solution with hydrazine gives good yields of amidrazones Scheme
Treatment of N-m-nitrophenylacetnitrazone with tin dichloride in hydrochloric acid afforded the reduced N1- m-aminophenyl acetamidrazone; however, it failed to produce any amidrazone Scheme Compound 14 was converted to the thioamide 15 in the presence of hydrogen sulfide Scheme The halogenation of alkyl- or aryl-amidines by using sodium hypochlorite in aqueous dimethyl sulfoxide solution affords the corresponding alkyl-, or arylhalodiazirine 41 Scheme Nucleophilic attack of hydrazine on a cyanamide can lead to amidrazone Scheme Organic Letters , 0 proofing DOI:
The intermediates B pick up cyanide anion from A to form product He has published 64 papers including 2 review articles. The Journal of Organic Chemistry , 75 4 , Schmidt, P.
Amidrazones are considered as precursors for preparing various triazoles Scheme American Cyanamid Co. A, , 4, Oxidation process is accompanied by a formal hydride transfer process generating species A and B Scheme Awarded with a scientific grant to be a scientific visitor to TU-Braunschweig, Germany from 28 November until 31 January Amidrazones Amidrazones are weak monoacid bases characterized by the structural formula 74, where R, R', R'', R''' and R'''' can be any of a wide variety of atomic or organic moieties.
Although N1-substituted amidrazones cannot form imideazides, they nevertheless form 2,5-disubstituted tetrazoles on treatment with nitrous acid Scheme Chemical Reviews , 7 , For more information, read Michigan Publishing's access and usage policy. Runner, M. Davidson, J.
The proposed mechanism for the formation of thiadiazoles 57 is thought to involve the initial oxidation of 49 by the acceptor Patent 3,,, ; Chem. He received his Ph. Thiele, J. Johnson, Yu Zhang, Richard P.